An increased risk of serious infections has been seen with the combination of TNF blockers with anakinra or abatacept, with no demonstrated added benefit in patients with RA. Drug interactions with biologic products: A higher rate of serious infections has been observed in RA patients treated with rituximab who received subsequent treatment with a TNF blocker.If an infection develops, monitor carefully and initiate appropriate therapy.Patients older than 65 years, patients with co-morbid conditions, and/or patients taking concomitant immunosuppressants may be at greater risk of infection.Do not start HUMIRA during an active infection, including localized infections.Monitor patients closely for the development of signs and symptoms of infection during and after treatment with HUMIRA, including the possible development of TB in patients who tested negative for latent TB infection prior to initiating therapy. with underlying conditions that may predispose them to infection. who resided in or traveled in regions where mycoses are endemic, 5. with a history of opportunistic infection, 4. Bacterial, viral, and other infections due to opportunistic pathogens, including Legionella and Listeria.Ĭarefully consider the risks and benefits of treatment with HUMIRA prior to initiating therapy in patients: 1.Consider empiric anti-fungal therapy in patients at risk for invasive fungal infections who develop severe systemic illness. Antigen and antibody testing for histoplasmosis may be negative in some patients with active infection. Patients with histoplasmosis or other invasive fungal infections may present with disseminated, rather than localized, disease. Invasive fungal infections, including histoplasmosis, coccidioidomycosis, candidiasis, aspergillosis, blastomycosis, and pneumocystosis.Initiate treatment for latent TB prior to HUMIRA use. Test patients for latent TB before HUMIRA use and during therapy. Patients with TB have frequently presented with disseminated or extrapulmonary disease. Active tuberculosis (TB), including reactivation of latent TB.Most patients who developed these infections were taking concomitant immunosuppressants such as methotrexate or corticosteroids.ĭiscontinue HUMIRA if a patient develops a serious infection or sepsis. Patients treated with HUMIRA are at increased risk for developing serious infections that may lead to hospitalization or death. IMPORTANT SAFETY INFORMATION for HUMIRA (adalimumab) 1 Patients can choose from personalized training provided by a nurse or online training videos.ĭirect your patients to step-by-step instruction videos for injecting HUMIRA. While patients will get their initial injection from a healthcare provider, a Nurse Ambassador can help reinforce training and provide ongoing support. Identifying ways to help save on the cost of HUMIRA.Navigating the insurance process by connecting the patient to an Insurance Specialist.With an average of 19 years of nursing experience, Nurse Ambassadors are the heart of HUMIRA Complete. ![]() Nurse Ambassadors † provide one-on-one support to help meet the unique needs of each individual patient. Insurance Specialists will continue to help patients understand their insurance coverage and potential options to save on HUMIRA. ![]() HUMIRA Complete provides your patients with the resources they need when they need them, throughout their whole treatment journey.
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